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There are numerous, well-documented health benefits of cistanche (scientifically known as 'Cistanche Tubulosa'), as well as the numerous compounds found within. Two of these compounds, Echinacoside and Acetoside (Verbsacoside) have been studied extensively.

Below, please find a selection of scientific studies and research articles* for your education.  

Cistanche Tubulosa

A Botanical Product Containing Cistanche and Ginkgo Extracts Potentially Improves Chronic Fatigue Syndrome Symptoms in Adults

A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue

A Review of Biologically Active Natural Products from a Desert Plant Cistanche tubulosa

Analysis of the active ingredients and health applications of cistanche

Anti-ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine

Antidepressant-Like Effects of Cistanche tubulosa Extract on Chronic Unpredictable Stress Rats

Botanicals as modulators of depression and mechanisms involved

Cistanche extracts ameliorates the neurotoxicity induced by hydrogen peroxide in new mutant DJ-1-transfected neuroblastoma cellular models

Cistanche promotes the adipogenesis of 3T3-L1 preadipocytes

Cistanche tubulosa ethanol extract mediates rat sex hormone levels by induction of testicular steroidgenic enzymes

Cistanche tubulosa phenylethanoid glycosides suppressed adipogenesis in 3T3-L1 adipocytes and improved obesity and insulin resistance

Cistanches Herba - An overview of its chemistry, pharmacology, and pharmacokinetics property

Cistanoside of Cistanche Herba ameliorates hypoxia-induced male reproductive damage via suppression of oxidative stress

Effect of Cistanche Tubulosa Extracts on Male Reproductive Function in Streptozotocin?Nicotinamide-Induced Diabetic Rats

Effect of PhenylEthanol Glycosides from Cistanche Tubulosa on Autophagy and Apoptosis in H22 Tumor-Bearing Mice

Effects of the Cistanche tubulosa Aqueous Extract on the Gut Microbiota of Mice with Intestinal Disorders

Herba Cistanche - A Review of Its Phytochemistry and Pharmacology

Herba Cistanche - One of the Best Pharmaceutical Gifts of Traditional Chinese Medicine

Herba Cistanches - Anti-aging Overview

Herba Cistanches stimulates cellular glutathione redox cycling by reactive oxygen species generated from mitochondrial respiration

Hypoglycemic and hypolipidemic effects of total glycosides of Cistanche tubulosa in diet streptozotocin-induced diabetic rats

Integrated network pharmacology to investigate dual-effects components of Cistanche tubulosa for treating both Osteoporosis and Alzheimer's Disease

Phenylethanol glycosides from Cistanche tubulosa improved reproductive dysfunction by regulating testicular steroids

Phenylethanol Glycosides from Cistanche tubulosa Suppress Hepatic Stellate Cell Activation and Block the Conduction of Signaling Pathways

Phenylethanol glycosides from Herba Cistanche improve the hypoxic tumor microenvironment and enhance the effects of oxaliplatin

Research Progress in the Effect of Traditional Chinese Medicine for Invigoration on Neurotransmitter Related Diseases

Reversal by aqueous extracts of Cistanche tubulosa from behavioral deficits in Alzheimer’s disease-like rat model

Roles of Chinese Medicine and Gut Microbiota in Chronic Constipation

Studies on Cistanches Herba - A Bibliometric Analysis

Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors

Echinacoside - a compound in Cistanche

Antiosteoporotic activity of echinacoside in ovariectomized rats

Anticancer effects of echinacoside in hepatocellular carcinoma mouse model and HepG2 cells

Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic Db-Db Mice

Echinacoside alleviated LPS-induced cell apoptosis and inflammation

Echinacoside Alleviates UVB Irradiation-Mediated Skin Damage via Inhibition of Oxidative Stress, DNA Damage, and Apoptosis

Echinacoside and Cistanche tubulosa ameliorate bisphenol A-induced testicular and sperm damage

Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation

Echinacoside exerts anti-tumor activity via the miR-503-3p TGF-beta1 Smad aixs in liver cancer

Echinacoside Improves Cognitive Impairment by Inhibiting Aß Deposition Through the PI3K AKT Nrf2 PPAR? Signaling Pathways in APP PS1 Mice

Echinacoside Increases Sperm Quantity in Rats by Targeting the Hypothalamic Androgen Receptor

Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1

Echinacoside inhibited cardiomyocyte pyroptosis and improved heart function

Echinacoside Isolated from Cistanche tubulosa Putatively Stimulates Growth Hormone Secretion

Echinacoside Isolated from Cistanche tubulosa Putatively Stimulates Growth Hormone Secretion via Activation of the Ghrelin Receptor

Echinacoside prevents hypoxic pulmonary hypertension by regulating the pulmonary artery function

Echinacoside Protects Against Dysfunction of Spermatogenesis Through the MAPK Signaling Pathway

Echinacoside Protects Dopaminergic Neurons Through Regulating IL-6JAK2STAT3 Pathway in Parkinson's Disease Model

Echinacoside Suppresses the Progression of Breast Cancer by Downregulating the Expression of miR-4306 and miR-4508

Echinacoside Upregulates Sirt1 to Suppress Endoplasmic Reticulum Stress and Inhibit Extracellular Matrix Degradation In Vitro and Ameliorates Osteoarthritis In Vivo

Echinacoside, a phenylethanoid glycoside from Cistanche deserticola, extends lifespan of Caenorhabditis elegans and protects from Aβ-induced toxicity

Echinacoside, an Active Constituent of Cistanche Herba, Exerts a Neuroprotective Effect

Echinacoside, an active constituent of Herba Cistanche, suppresses epileptiform activity in hippocampal CA3 pyramidal neurons

Echinacoside, an Inestimable Natural Product in Treatment of Neurological and other Disorders

Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease

Neuroprotective Effects and Related Mechanisms of Echinacoside in MPTP-Induced PD Mice

The potential effects and mechanism of echinacoside powder in the treatment of Hirschsprung's Disease

Therapeutic Potential and Molecular Mechanisms of Echinacoside in Neurodegenerative Diseases

Acteoside (Verbascoside) - a compound in Cistanche

Acteoside (Verbascoside) attenuates experimental varicocele-induced damage to testes and sperm levels

Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1TLR4TREM1 signaling pathway

Acteoside ameliorates inflammatory responses through NFkB pathway in alcohol induced hepatic damage

Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis

Acteoside as a potential therapeutic option for primary hepatocellular carcinoma

Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease

Acteoside exerts neuroprotection effects in the model of Parkinson's disease via inducing autophagy

Acteoside inhibits autophagic apoptosis of retinal ganglion cells to rescue glaucoma-induced optic atrophy

Acteoside protects against 6-OHDA-induced dopaminergic neuron damage via Nrf2-ARE signaling pathway

Acteoside relieves mesangial cell injury by regulating Th22 cell chemotaxis and proliferation in IgA nephropathy

Acteoside-improved streptozotocin-induced learning and memory impairment by upregulating hippocampal insulin, glucose transport, and energy metabolism

Advanced research on acteoside for chemistry and bioactivities

Synergistic anticancer effect of acteoside and temozolomide-based glioblastoma chemotherapy

The Mechanism of Memory Enhancement of Acteoside (Verbascoside) in the Senescent Mouse Model

The pharmacokinetic property and pharmacological activity of acteoside - A review

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